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Pasdium Brand names, Pasdium Analogs

Pasdium Brand Names Mixture

  • No information avaliable

Pasdium Chemical_Formula

C7H7NO3

Pasdium RX_link

http://www.rxlist.com/cgi/generic2/paser.htm

Pasdium fda sheet

Pasdium msds (material safety sheet)

Pasdium MSDS

Pasdium Synthesis Reference

Biniecki S., et al. Acta Pol Pharm. 1967;24(5):469-73

Pasdium Molecular Weight

153.135 g/mol

Pasdium Melting Point

150.5 oC

Pasdium H2O Solubility

1690 mg/L

Pasdium State

Solid

Pasdium LogP

1.012

Pasdium Dosage Forms

Packet of coated granules

Pasdium Indication

For the treatment of tuberculosis

Pasdium Pharmacology

Aminosalicylic acid is an anti-mycobacterial agent used with other anti-tuberculosis drugs (most often isoniazid) for the treatment of all forms of active tuberculosis due to susceptible strains of tubercle bacilli. The two major considerations in the clinical pharmacology of aminosalicylic acid are the prompt production of a toxic inactive metabolite under acid conditions and the short serum half life of one hour for the free drug. Aminosalicylic acid is bacteriostatic against Mycobacterium tuberculosis (prevents the multiplying of bacteria without destroying them). It also inhibits the onset of bacterial resistance to streptomycin and isoniazid.

Pasdium Absorption

No information avaliable

Pasdium side effects and Toxicity

LD50=4 gm/kg (orally in mice); LD50=3650 mg/kg (orally in rabbits)

Pasdium Patient Information

Pasdium Organisms Affected

Mycobacteria