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Propasa Brand names, Propasa Analogs

Propasa Brand Names Mixture

  • No information avaliable

Propasa Chemical_Formula

C7H7NO3

Propasa RX_link

http://www.rxlist.com/cgi/generic2/paser.htm

Propasa fda sheet

Propasa msds (material safety sheet)

Propasa MSDS

Propasa Synthesis Reference

Biniecki S., et al. Acta Pol Pharm. 1967;24(5):469-73

Propasa Molecular Weight

153.135 g/mol

Propasa Melting Point

150.5 oC

Propasa H2O Solubility

1690 mg/L

Propasa State

Solid

Propasa LogP

1.012

Propasa Dosage Forms

Packet of coated granules

Propasa Indication

For the treatment of tuberculosis

Propasa Pharmacology

Aminosalicylic acid is an anti-mycobacterial agent used with other anti-tuberculosis drugs (most often isoniazid) for the treatment of all forms of active tuberculosis due to susceptible strains of tubercle bacilli. The two major considerations in the clinical pharmacology of aminosalicylic acid are the prompt production of a toxic inactive metabolite under acid conditions and the short serum half life of one hour for the free drug. Aminosalicylic acid is bacteriostatic against Mycobacterium tuberculosis (prevents the multiplying of bacteria without destroying them). It also inhibits the onset of bacterial resistance to streptomycin and isoniazid.

Propasa Absorption

No information avaliable

Propasa side effects and Toxicity

LD50=4 gm/kg (orally in mice); LD50=3650 mg/kg (orally in rabbits)

Propasa Patient Information

Propasa Organisms Affected

Mycobacteria