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Pamacyl Brand names, Pamacyl Analogs

Pamacyl Brand Names Mixture

  • No information avaliable

Pamacyl Chemical_Formula

C7H7NO3

Pamacyl RX_link

http://www.rxlist.com/cgi/generic2/paser.htm

Pamacyl fda sheet

Pamacyl msds (material safety sheet)

Pamacyl MSDS

Pamacyl Synthesis Reference

Biniecki S., et al. Acta Pol Pharm. 1967;24(5):469-73

Pamacyl Molecular Weight

153.135 g/mol

Pamacyl Melting Point

150.5 oC

Pamacyl H2O Solubility

1690 mg/L

Pamacyl State

Solid

Pamacyl LogP

1.012

Pamacyl Dosage Forms

Packet of coated granules

Pamacyl Indication

For the treatment of tuberculosis

Pamacyl Pharmacology

Aminosalicylic acid is an anti-mycobacterial agent used with other anti-tuberculosis drugs (most often isoniazid) for the treatment of all forms of active tuberculosis due to susceptible strains of tubercle bacilli. The two major considerations in the clinical pharmacology of aminosalicylic acid are the prompt production of a toxic inactive metabolite under acid conditions and the short serum half life of one hour for the free drug. Aminosalicylic acid is bacteriostatic against Mycobacterium tuberculosis (prevents the multiplying of bacteria without destroying them). It also inhibits the onset of bacterial resistance to streptomycin and isoniazid.

Pamacyl Absorption

No information avaliable

Pamacyl side effects and Toxicity

LD50=4 gm/kg (orally in mice); LD50=3650 mg/kg (orally in rabbits)

Pamacyl Patient Information

Pamacyl Organisms Affected

Mycobacteria