Aminox en es it fr

Aminox Brand names, Aminox Analogs

Aminox Brand Names Mixture

  • No information avaliable

Aminox Chemical_Formula

C7H7NO3

Aminox RX_link

http://www.rxlist.com/cgi/generic2/paser.htm

Aminox fda sheet

Aminox msds (material safety sheet)

Aminox MSDS

Aminox Synthesis Reference

Biniecki S., et al. Acta Pol Pharm. 1967;24(5):469-73

Aminox Molecular Weight

153.135 g/mol

Aminox Melting Point

150.5 oC

Aminox H2O Solubility

1690 mg/L

Aminox State

Solid

Aminox LogP

1.012

Aminox Dosage Forms

Packet of coated granules

Aminox Indication

For the treatment of tuberculosis

Aminox Pharmacology

Aminosalicylic acid is an anti-mycobacterial agent used with other anti-tuberculosis drugs (most often isoniazid) for the treatment of all forms of active tuberculosis due to susceptible strains of tubercle bacilli. The two major considerations in the clinical pharmacology of aminosalicylic acid are the prompt production of a toxic inactive metabolite under acid conditions and the short serum half life of one hour for the free drug. Aminosalicylic acid is bacteriostatic against Mycobacterium tuberculosis (prevents the multiplying of bacteria without destroying them). It also inhibits the onset of bacterial resistance to streptomycin and isoniazid.

Aminox Absorption

No information avaliable

Aminox side effects and Toxicity

LD50=4 gm/kg (orally in mice); LD50=3650 mg/kg (orally in rabbits)

Aminox Patient Information

Aminox Organisms Affected

Mycobacteria