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Entepas Brand names, Entepas Analogs

Entepas Brand Names Mixture

  • No information avaliable

Entepas Chemical_Formula

C7H7NO3

Entepas RX_link

http://www.rxlist.com/cgi/generic2/paser.htm

Entepas fda sheet

Entepas msds (material safety sheet)

Entepas MSDS

Entepas Synthesis Reference

Biniecki S., et al. Acta Pol Pharm. 1967;24(5):469-73

Entepas Molecular Weight

153.135 g/mol

Entepas Melting Point

150.5 oC

Entepas H2O Solubility

1690 mg/L

Entepas State

Solid

Entepas LogP

1.012

Entepas Dosage Forms

Packet of coated granules

Entepas Indication

For the treatment of tuberculosis

Entepas Pharmacology

Aminosalicylic acid is an anti-mycobacterial agent used with other anti-tuberculosis drugs (most often isoniazid) for the treatment of all forms of active tuberculosis due to susceptible strains of tubercle bacilli. The two major considerations in the clinical pharmacology of aminosalicylic acid are the prompt production of a toxic inactive metabolite under acid conditions and the short serum half life of one hour for the free drug. Aminosalicylic acid is bacteriostatic against Mycobacterium tuberculosis (prevents the multiplying of bacteria without destroying them). It also inhibits the onset of bacterial resistance to streptomycin and isoniazid.

Entepas Absorption

No information avaliable

Entepas side effects and Toxicity

LD50=4 gm/kg (orally in mice); LD50=3650 mg/kg (orally in rabbits)

Entepas Patient Information

Entepas Organisms Affected

Mycobacteria