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PASK Brand names, PASK Analogs

PASK Brand Names Mixture

  • No information avaliable

PASK Chemical_Formula

C7H7NO3

PASK RX_link

http://www.rxlist.com/cgi/generic2/paser.htm

PASK fda sheet

PASK msds (material safety sheet)

PASK MSDS

PASK Synthesis Reference

Biniecki S., et al. Acta Pol Pharm. 1967;24(5):469-73

PASK Molecular Weight

153.135 g/mol

PASK Melting Point

150.5 oC

PASK H2O Solubility

1690 mg/L

PASK State

Solid

PASK LogP

1.012

PASK Dosage Forms

Packet of coated granules

PASK Indication

For the treatment of tuberculosis

PASK Pharmacology

Aminosalicylic acid is an anti-mycobacterial agent used with other anti-tuberculosis drugs (most often isoniazid) for the treatment of all forms of active tuberculosis due to susceptible strains of tubercle bacilli. The two major considerations in the clinical pharmacology of aminosalicylic acid are the prompt production of a toxic inactive metabolite under acid conditions and the short serum half life of one hour for the free drug. Aminosalicylic acid is bacteriostatic against Mycobacterium tuberculosis (prevents the multiplying of bacteria without destroying them). It also inhibits the onset of bacterial resistance to streptomycin and isoniazid.

PASK Absorption

No information avaliable

PASK side effects and Toxicity

LD50=4 gm/kg (orally in mice); LD50=3650 mg/kg (orally in rabbits)

PASK Patient Information

PASK Organisms Affected

Mycobacteria