Pasa
Pasa Brand names, Pasa Analogs
- Aminosalicylate Sodium
- Amino-Pas
- Aminopar
- Aminox
- Apacil
- Apas
- Deapasil
- Entepas
- Ferrosan
- Gabbropas
- Hellipidyl
- Kyselina P-Aminosalicylova
- Neopasalate
- Osacyl
- P-Aminosalicylic Acid
- PAS
- PAS-C
- PASK
- Pamacyl
- Pamisyl
- Para-Amino Salicylic Acid
- Para-Pas
- Paramycin
- Parasal
- Parasalicil
- Parasalindon
- Pasa
- Pasalon
- Pasara
- Pascorbic
- Pasdium
- Pasem
- Paser
- Pasmed
- Pasnodia
- Pasolac
- Propasa
- Rezipas
- Sanipirol-4
- Sanipriol-4
Pasa Brand Names Mixture
- No information avaliable
Pasa Chemical_Formula
C7H7NO3
Pasa RX_link
http://www.rxlist.com/cgi/generic2/paser.htm
Pasa fda sheet
Pasa msds (material safety sheet)
Pasa Synthesis Reference
Biniecki S., et al. Acta Pol Pharm. 1967;24(5):469-73
Pasa Molecular Weight
153.135 g/mol
Pasa Melting Point
150.5 oC
Pasa H2O Solubility
1690 mg/L
Pasa State
Solid
Pasa LogP
1.012
Pasa Dosage Forms
Packet of coated granules
Pasa Indication
For the treatment of tuberculosis
Pasa Pharmacology
Aminosalicylic acid is an anti-mycobacterial agent used with other anti-tuberculosis drugs (most often isoniazid) for the treatment of all forms of active tuberculosis due to susceptible strains of tubercle bacilli. The two major considerations in the clinical pharmacology of aminosalicylic acid are the prompt production of a toxic inactive metabolite under acid conditions and the short serum half life of one hour for the free drug. Aminosalicylic acid is bacteriostatic against Mycobacterium tuberculosis (prevents the multiplying of bacteria without destroying them). It also inhibits the onset of bacterial resistance to streptomycin and isoniazid.
Pasa Absorption
No information avaliable
Pasa side effects and Toxicity
LD50=4 gm/kg (orally in mice); LD50=3650 mg/kg (orally in rabbits)
Pasa Patient Information
Pasa Organisms Affected
Mycobacteria
