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PAS-C Brand names, PAS-C Analogs

PAS-C Brand Names Mixture

  • No information avaliable

PAS-C Chemical_Formula

C7H7NO3

PAS-C RX_link

http://www.rxlist.com/cgi/generic2/paser.htm

PAS-C fda sheet

PAS-C msds (material safety sheet)

PAS-C MSDS

PAS-C Synthesis Reference

Biniecki S., et al. Acta Pol Pharm. 1967;24(5):469-73

PAS-C Molecular Weight

153.135 g/mol

PAS-C Melting Point

150.5 oC

PAS-C H2O Solubility

1690 mg/L

PAS-C State

Solid

PAS-C LogP

1.012

PAS-C Dosage Forms

Packet of coated granules

PAS-C Indication

For the treatment of tuberculosis

PAS-C Pharmacology

Aminosalicylic acid is an anti-mycobacterial agent used with other anti-tuberculosis drugs (most often isoniazid) for the treatment of all forms of active tuberculosis due to susceptible strains of tubercle bacilli. The two major considerations in the clinical pharmacology of aminosalicylic acid are the prompt production of a toxic inactive metabolite under acid conditions and the short serum half life of one hour for the free drug. Aminosalicylic acid is bacteriostatic against Mycobacterium tuberculosis (prevents the multiplying of bacteria without destroying them). It also inhibits the onset of bacterial resistance to streptomycin and isoniazid.

PAS-C Absorption

No information avaliable

PAS-C side effects and Toxicity

LD50=4 gm/kg (orally in mice); LD50=3650 mg/kg (orally in rabbits)

PAS-C Patient Information

PAS-C Organisms Affected

Mycobacteria