meso-Nordihydroguaiaretic acid
meso-Nordihydroguaiaretic acid Brand names, meso-Nordihydroguaiaretic acid Analogs
meso-Nordihydroguaiaretic acid Brand Names Mixture
- No information avaliable
meso-Nordihydroguaiaretic acid Chemical_Formula
C22H30O3
meso-Nordihydroguaiaretic acid RX_link
http://www.rxlist.com/cgi/generic4/megace_es.htm
meso-Nordihydroguaiaretic acid fda sheet
meso-Nordihydroguaiaretic acid msds (material safety sheet)
meso-Nordihydroguaiaretic acid Synthesis Reference
No information avaliable
meso-Nordihydroguaiaretic acid Molecular Weight
342.472 g/mol
meso-Nordihydroguaiaretic acid Melting Point
218.0-220.0oC
meso-Nordihydroguaiaretic acid H2O Solubility
2 µg/mL (at 37°C for the acetate salt)
meso-Nordihydroguaiaretic acid State
Solid
meso-Nordihydroguaiaretic acid LogP
3.123
meso-Nordihydroguaiaretic acid Dosage Forms
Oral suspension containing 125 mg of megestrol acetate per mL; Tablet
meso-Nordihydroguaiaretic acid Indication
For the treatment of anorexia, cachexia, or an unexplained, significant weight loss in patients with a diagnosis of acquired immunodeficiency syndrome (AIDS). Also used to treat breast cancer, endometrial cancer, and prostate cancer in Canada and some other countries.
meso-Nordihydroguaiaretic acid Pharmacology
Megestrol is a synthetic progestin and has the same physiologic effects as natural progesterone. The precise mechanism of megestrol’s antianorexic and anticachetic effects is unknown. Initially developed as a contraceptive, it was first evaluated in breast cancer treatment in 1967.
meso-Nordihydroguaiaretic acid Absorption
Variable, but well absorbed orally.
meso-Nordihydroguaiaretic acid side effects and Toxicity
No serious unexpected side effects have resulted from studies involving megestrol acetate oral suspension administered in dosages as high as 1200 mg/day.
meso-Nordihydroguaiaretic acid Patient Information
No information avaliable
meso-Nordihydroguaiaretic acid Organisms Affected
Humans and other mammals
