Nordihydroguaiaretic acid
Nordihydroguaiaretic acid Brand names, Nordihydroguaiaretic acid Analogs
Nordihydroguaiaretic acid Brand Names Mixture
- No information avaliable
Nordihydroguaiaretic acid Chemical_Formula
C22H30O3
Nordihydroguaiaretic acid RX_link
http://www.rxlist.com/cgi/generic4/megace_es.htm
Nordihydroguaiaretic acid fda sheet
Nordihydroguaiaretic acid msds (material safety sheet)
Nordihydroguaiaretic acid Synthesis Reference
No information avaliable
Nordihydroguaiaretic acid Molecular Weight
342.472 g/mol
Nordihydroguaiaretic acid Melting Point
218.0-220.0oC
Nordihydroguaiaretic acid H2O Solubility
2 µg/mL (at 37°C for the acetate salt)
Nordihydroguaiaretic acid State
Solid
Nordihydroguaiaretic acid LogP
3.123
Nordihydroguaiaretic acid Dosage Forms
Oral suspension containing 125 mg of megestrol acetate per mL; Tablet
Nordihydroguaiaretic acid Indication
For the treatment of anorexia, cachexia, or an unexplained, significant weight loss in patients with a diagnosis of acquired immunodeficiency syndrome (AIDS). Also used to treat breast cancer, endometrial cancer, and prostate cancer in Canada and some other countries.
Nordihydroguaiaretic acid Pharmacology
Megestrol is a synthetic progestin and has the same physiologic effects as natural progesterone. The precise mechanism of megestrol’s antianorexic and anticachetic effects is unknown. Initially developed as a contraceptive, it was first evaluated in breast cancer treatment in 1967.
Nordihydroguaiaretic acid Absorption
Variable, but well absorbed orally.
Nordihydroguaiaretic acid side effects and Toxicity
No serious unexpected side effects have resulted from studies involving megestrol acetate oral suspension administered in dosages as high as 1200 mg/day.
Nordihydroguaiaretic acid Patient Information
No information avaliable
Nordihydroguaiaretic acid Organisms Affected
Humans and other mammals
