Actinex
Actinex Brand names, Actinex Analogs
Actinex Brand Names Mixture
- No information avaliable
Actinex Chemical_Formula
C22H30O3
Actinex RX_link
http://www.rxlist.com/cgi/generic4/megace_es.htm
Actinex fda sheet
Actinex msds (material safety sheet)
Actinex Synthesis Reference
No information avaliable
Actinex Molecular Weight
342.472 g/mol
Actinex Melting Point
218.0-220.0oC
Actinex H2O Solubility
2 µg/mL (at 37°C for the acetate salt)
Actinex State
Solid
Actinex LogP
3.123
Actinex Dosage Forms
Oral suspension containing 125 mg of megestrol acetate per mL; Tablet
Actinex Indication
For the treatment of anorexia, cachexia, or an unexplained, significant weight loss in patients with a diagnosis of acquired immunodeficiency syndrome (AIDS). Also used to treat breast cancer, endometrial cancer, and prostate cancer in Canada and some other countries.
Actinex Pharmacology
Megestrol is a synthetic progestin and has the same physiologic effects as natural progesterone. The precise mechanism of megestrol’s antianorexic and anticachetic effects is unknown. Initially developed as a contraceptive, it was first evaluated in breast cancer treatment in 1967.
Actinex Absorption
Variable, but well absorbed orally.
Actinex side effects and Toxicity
No serious unexpected side effects have resulted from studies involving megestrol acetate oral suspension administered in dosages as high as 1200 mg/day.
Actinex Patient Information
No information avaliable
Actinex Organisms Affected
Humans and other mammals
