HMD
Categoria
HMD Marchi, HMD Analoghi
HMD Marchi miscela
HMD Formula chimica
C10H14N2O4
HMD RX link
http://www.rxlist.com/cgi/generic/sinemet.htm
HMD FDA foglio
HMD DMS (foglio di materiale di sicurezza)
HMD Sintesi di riferimento
Chemerda et al. US Pat. 3,462,536 (1963)
HMD Peso molecolare
226.229 g/mol
HMD Temperatura di fusione
203-205oC
HMD H2O Solubilita
3,8 mg / L
HMD Stato
Solid
HMD LogP
0.494
HMD Forme di dosaggio
Compressa (25 mg)
HMD Indicazione
Per il trattamento dei sintomi del morbo di Parkinson idiopatico (paralisi agitante), post-encefalitiche parkinsonismo
HMD Farmacologia
Carbidopa, un inibitore della decarbossilasi non competitivo, è usato in associazione con levodopa per il trattamento del morbo di Parkinson.
HMD Assorbimento
Rapidamente decarbossilata a dopamina nei tessuti extracerebrali in modo che solo una piccola porzione di una data dose viene trasportato invariato al sistema nervoso centrale.
HMD Tossicita
I sintomi di una tossicità carbidopa includono spasmi muscolari, debolezza, spasmi delle palpebre, nausea, vomito, diarrea, un battito cardiaco irregolare, confusione, agitazione, allucinazioni e perdita di coscienza.
HMD Informazioni paziente
Carbidopa is used with levodopa to treat Parkinson's disease. Parkinson's disease
is believed to be related to low levels of a chemical called dopamine (DOE pa meen)
in the brain. Levodopa (Dopar, Larodopa) is turned into dopamine in the body.
Carbidopa is used with levodopa to prevent the breakdown (metabolism) of levodopa
before it can reach the brain and take effect. Carbidopa is only effective if it is
taken with levodopa. It has no effect if it is used alone. Carbidopa is used with
levodopa to treat the stiffness, tremors, spasms, and poor muscle control of
Parkinson's disease. These medications are also used to treat the same muscular
conditions when they are caused by drugs such as chlorpromazine (Thorazine),
fluphenazine (Prolixin), perphenazine (Trilafon), and others.
is believed to be related to low levels of a chemical called dopamine (DOE pa meen)
in the brain. Levodopa (Dopar, Larodopa) is turned into dopamine in the body.
Carbidopa is used with levodopa to prevent the breakdown (metabolism) of levodopa
before it can reach the brain and take effect. Carbidopa is only effective if it is
taken with levodopa. It has no effect if it is used alone. Carbidopa is used with
levodopa to treat the stiffness, tremors, spasms, and poor muscle control of
Parkinson's disease. These medications are also used to treat the same muscular
conditions when they are caused by drugs such as chlorpromazine (Thorazine),
fluphenazine (Prolixin), perphenazine (Trilafon), and others.
HMD Atto interessato organismi
Gli esseri umani e altri mammiferi
