Carbidopa Anhydrous
Carbidopa Anhydrous Brand names, Carbidopa Anhydrous Analogs
Carbidopa Anhydrous Brand Names Mixture
- Atamet (carbidopa + levodopa)
- Sinemet (carbidopa + levodopa)
Carbidopa Anhydrous Chemical_Formula
C10H14N2O4
Carbidopa Anhydrous RX_link
http://www.rxlist.com/cgi/generic/sinemet.htm
Carbidopa Anhydrous fda sheet
Carbidopa Anhydrous msds (material safety sheet)
Carbidopa Anhydrous Synthesis Reference
Chemerda et al., U.S. Pat. 3,462,536 (1963)
Carbidopa Anhydrous Molecular Weight
226.229 g/mol
Carbidopa Anhydrous Melting Point
203-205oC
Carbidopa Anhydrous H2O Solubility
3.8 mg/L
Carbidopa Anhydrous State
Solid
Carbidopa Anhydrous LogP
0.494
Carbidopa Anhydrous Dosage Forms
Tablet (25 mg)
Carbidopa Anhydrous Indication
For treatment of the symptoms of idiopathic Parkinson's disease (paralysis agitans), post-encephalitic parkinsonism
Carbidopa Anhydrous Pharmacology
Carbidopa, a noncompetitive decarboxylase inhibitor, is used in combination with levodopa for the treatment of Parkinson's disease.
Carbidopa Anhydrous Absorption
Rapidly decarboxylated to dopamine in extracerebral tissues so that only a small portion of a given dose is transported unchanged to the central nervous system.
Carbidopa Anhydrous side effects and Toxicity
Symptoms of a carbidopa toxicity include muscle spasms or weakness, spasms of the eyelid, nausea, vomiting, diarrhea, an irregular heartbeat, confusion, agitation, hallucinations, and unconsciousness.
Carbidopa Anhydrous Patient Information
Carbidopa is used with levodopa to treat Parkinson's disease. Parkinson's disease
is believed to be related to low levels of a chemical called dopamine (DOE pa meen)
in the brain. Levodopa (Dopar, Larodopa) is turned into dopamine in the body.
Carbidopa is used with levodopa to prevent the breakdown (metabolism) of levodopa
before it can reach the brain and take effect. Carbidopa is only effective if it is
taken with levodopa. It has no effect if it is used alone. Carbidopa is used with
levodopa to treat the stiffness, tremors, spasms, and poor muscle control of
Parkinson's disease. These medications are also used to treat the same muscular
conditions when they are caused by drugs such as chlorpromazine (Thorazine),
fluphenazine (Prolixin), perphenazine (Trilafon), and others.
is believed to be related to low levels of a chemical called dopamine (DOE pa meen)
in the brain. Levodopa (Dopar, Larodopa) is turned into dopamine in the body.
Carbidopa is used with levodopa to prevent the breakdown (metabolism) of levodopa
before it can reach the brain and take effect. Carbidopa is only effective if it is
taken with levodopa. It has no effect if it is used alone. Carbidopa is used with
levodopa to treat the stiffness, tremors, spasms, and poor muscle control of
Parkinson's disease. These medications are also used to treat the same muscular
conditions when they are caused by drugs such as chlorpromazine (Thorazine),
fluphenazine (Prolixin), perphenazine (Trilafon), and others.
Carbidopa Anhydrous Organisms Affected
Humans and other mammals
