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Atamet Brand names, Atamet Analogs

Atamet Brand Names Mixture

  • Atamet (carbidopa + levodopa)
  • Sinemet (carbidopa + levodopa)

Atamet Chemical_Formula

C10H14N2O4

Atamet RX_link

http://www.rxlist.com/cgi/generic/sinemet.htm

Atamet fda sheet

Atamet msds (material safety sheet)

Atamet Synthesis Reference

Chemerda et al., U.S. Pat. 3,462,536 (1963)

Atamet Molecular Weight

226.229 g/mol

Atamet Melting Point

203-205oC

Atamet H2O Solubility

3.8 mg/L

Atamet State

Solid

Atamet LogP

0.494

Atamet Dosage Forms

Tablet (25 mg)

Atamet Indication

For treatment of the symptoms of idiopathic Parkinson's disease (paralysis agitans), post-encephalitic parkinsonism

Atamet Pharmacology

Carbidopa, a noncompetitive decarboxylase inhibitor, is used in combination with levodopa for the treatment of Parkinson's disease.

Atamet Absorption

Rapidly decarboxylated to dopamine in extracerebral tissues so that only a small portion of a given dose is transported unchanged to the central nervous system.

Atamet side effects and Toxicity

Symptoms of a carbidopa toxicity include muscle spasms or weakness, spasms of the eyelid, nausea, vomiting, diarrhea, an irregular heartbeat, confusion, agitation, hallucinations, and unconsciousness.

Atamet Patient Information

Carbidopa is used with levodopa to treat Parkinson's disease. Parkinson's disease
is believed to be related to low levels of a chemical called dopamine (DOE pa meen)
in the brain. Levodopa (Dopar, Larodopa) is turned into dopamine in the body.
Carbidopa is used with levodopa to prevent the breakdown (metabolism) of levodopa
before it can reach the brain and take effect. Carbidopa is only effective if it is
taken with levodopa. It has no effect if it is used alone. Carbidopa is used with
levodopa to treat the stiffness, tremors, spasms, and poor muscle control of
Parkinson's disease. These medications are also used to treat the same muscular
conditions when they are caused by drugs such as chlorpromazine (Thorazine),
fluphenazine (Prolixin), perphenazine (Trilafon), and others.

Atamet Organisms Affected

Humans and other mammals