Alpha-Methyldopahydrazine en es it fr

Alpha-Methyldopahydrazine Brand names, Alpha-Methyldopahydrazine Analogs

Alpha-Methyldopahydrazine Brand Names Mixture

  • Atamet (carbidopa + levodopa)
  • Sinemet (carbidopa + levodopa)

Alpha-Methyldopahydrazine Chemical_Formula


Alpha-Methyldopahydrazine RX_link

Alpha-Methyldopahydrazine fda sheet

Alpha-Methyldopahydrazine msds (material safety sheet)

Alpha-Methyldopahydrazine Synthesis Reference

Chemerda et al., U.S. Pat. 3,462,536 (1963)

Alpha-Methyldopahydrazine Molecular Weight

226.229 g/mol

Alpha-Methyldopahydrazine Melting Point


Alpha-Methyldopahydrazine H2O Solubility

3.8 mg/L

Alpha-Methyldopahydrazine State


Alpha-Methyldopahydrazine LogP


Alpha-Methyldopahydrazine Dosage Forms

Tablet (25 mg)

Alpha-Methyldopahydrazine Indication

For treatment of the symptoms of idiopathic Parkinson's disease (paralysis agitans), post-encephalitic parkinsonism

Alpha-Methyldopahydrazine Pharmacology

Carbidopa, a noncompetitive decarboxylase inhibitor, is used in combination with levodopa for the treatment of Parkinson's disease.

Alpha-Methyldopahydrazine Absorption

Rapidly decarboxylated to dopamine in extracerebral tissues so that only a small portion of a given dose is transported unchanged to the central nervous system.

Alpha-Methyldopahydrazine side effects and Toxicity

Symptoms of a carbidopa toxicity include muscle spasms or weakness, spasms of the eyelid, nausea, vomiting, diarrhea, an irregular heartbeat, confusion, agitation, hallucinations, and unconsciousness.

Alpha-Methyldopahydrazine Patient Information

Carbidopa is used with levodopa to treat Parkinson's disease. Parkinson's disease
is believed to be related to low levels of a chemical called dopamine (DOE pa meen)
in the brain. Levodopa (Dopar, Larodopa) is turned into dopamine in the body.
Carbidopa is used with levodopa to prevent the breakdown (metabolism) of levodopa
before it can reach the brain and take effect. Carbidopa is only effective if it is
taken with levodopa. It has no effect if it is used alone. Carbidopa is used with
levodopa to treat the stiffness, tremors, spasms, and poor muscle control of
Parkinson's disease. These medications are also used to treat the same muscular
conditions when they are caused by drugs such as chlorpromazine (Thorazine),
fluphenazine (Prolixin), perphenazine (Trilafon), and others.

Alpha-Methyldopahydrazine Organisms Affected

Humans and other mammals