Tubophan
Brand names,
Tubophan
Analogs
Tubophan
Brand Names Mixture
Tubophan
Chemical_Formula
C13H19NO4S
Tubophan
RX_link
http://www.rxlist.com/cgi/generic/colbenemid.htm
Tubophan
fda sheet
Tubophan
msds (material safety sheet)
Tubophan
Synthesis Reference
No information avaliable
Tubophan
Molecular Weight
285.36 g/mol
Tubophan
Melting Point
195 oC
Tubophan
H2O Solubility
27.1 mg/L
Tubophan
State
Solid
Tubophan
LogP
2.324
Tubophan
Dosage Forms
Tablet
Tubophan
Indication
For the treatment of gout and high levels of uric acid in the blood
Tubophan
Pharmacology
Probenecid is a uricosuric and renal tubular blocking agent and is used in combination with colchicine to treat chronic gouty arthritis when complicated by frequent, recurrent acute attacks of gout. It inhibits the tubular reabsorption of urate, thus increasing the urinary excretion of uric acid and decreasing serum urate levels. Effective uricosuria reduces the miscible urate pool, retards urate deposition, and promotes resorption of urate deposits.
Tubophan
Absorption
No information avaliable
Tubophan
side effects and Toxicity
No information avaliable
Tubophan
Patient Information
No information avaliable
Tubophan
Organisms Affected
Humans and other mammals