Col-Probenecid
Brand names,
Col-Probenecid
Analogs
Col-Probenecid
Brand Names Mixture
Col-Probenecid
Chemical_Formula
C13H19NO4S
Col-Probenecid
RX_link
http://www.rxlist.com/cgi/generic/colbenemid.htm
Col-Probenecid
fda sheet
Col-Probenecid
msds (material safety sheet)
Col-Probenecid
Synthesis Reference
No information avaliable
Col-Probenecid
Molecular Weight
285.36 g/mol
Col-Probenecid
Melting Point
195 oC
Col-Probenecid
H2O Solubility
27.1 mg/L
Col-Probenecid
State
Solid
Col-Probenecid
LogP
2.324
Col-Probenecid
Dosage Forms
Tablet
Col-Probenecid
Indication
For the treatment of gout and high levels of uric acid in the blood
Col-Probenecid
Pharmacology
Probenecid is a uricosuric and renal tubular blocking agent and is used in combination with colchicine to treat chronic gouty arthritis when complicated by frequent, recurrent acute attacks of gout. It inhibits the tubular reabsorption of urate, thus increasing the urinary excretion of uric acid and decreasing serum urate levels. Effective uricosuria reduces the miscible urate pool, retards urate deposition, and promotes resorption of urate deposits.
Col-Probenecid
Absorption
No information avaliable
Col-Probenecid
side effects and Toxicity
No information avaliable
Col-Probenecid
Patient Information
No information avaliable
Col-Probenecid
Organisms Affected
Humans and other mammals