Probalan
Brand names,
Probalan
Analogs
Probalan
Brand Names Mixture
Probalan
Chemical_Formula
C13H19NO4S
Probalan
RX_link
http://www.rxlist.com/cgi/generic/colbenemid.htm
Probalan
fda sheet
Probalan
msds (material safety sheet)
Probalan
Synthesis Reference
No information avaliable
Probalan
Molecular Weight
285.36 g/mol
Probalan
Melting Point
195 oC
Probalan
H2O Solubility
27.1 mg/L
Probalan
State
Solid
Probalan
LogP
2.324
Probalan
Dosage Forms
Tablet
Probalan
Indication
For the treatment of gout and high levels of uric acid in the blood
Probalan
Pharmacology
Probenecid is a uricosuric and renal tubular blocking agent and is used in combination with colchicine to treat chronic gouty arthritis when complicated by frequent, recurrent acute attacks of gout. It inhibits the tubular reabsorption of urate, thus increasing the urinary excretion of uric acid and decreasing serum urate levels. Effective uricosuria reduces the miscible urate pool, retards urate deposition, and promotes resorption of urate deposits.
Probalan
Absorption
No information avaliable
Probalan
side effects and Toxicity
No information avaliable
Probalan
Patient Information
No information avaliable
Probalan
Organisms Affected
Humans and other mammals