Proben-C
Brand names,
Proben-C
Analogs
Proben-C
Brand Names Mixture
Proben-C
Chemical_Formula
C13H19NO4S
Proben-C
RX_link
http://www.rxlist.com/cgi/generic/colbenemid.htm
Proben-C
fda sheet
Proben-C
msds (material safety sheet)
Proben-C
Synthesis Reference
No information avaliable
Proben-C
Molecular Weight
285.36 g/mol
Proben-C
Melting Point
195 oC
Proben-C
H2O Solubility
27.1 mg/L
Proben-C
State
Solid
Proben-C
LogP
2.324
Proben-C
Dosage Forms
Tablet
Proben-C
Indication
For the treatment of gout and high levels of uric acid in the blood
Proben-C
Pharmacology
Probenecid is a uricosuric and renal tubular blocking agent and is used in combination with colchicine to treat chronic gouty arthritis when complicated by frequent, recurrent acute attacks of gout. It inhibits the tubular reabsorption of urate, thus increasing the urinary excretion of uric acid and decreasing serum urate levels. Effective uricosuria reduces the miscible urate pool, retards urate deposition, and promotes resorption of urate deposits.
Proben-C
Absorption
No information avaliable
Proben-C
side effects and Toxicity
No information avaliable
Proben-C
Patient Information
No information avaliable
Proben-C
Organisms Affected
Humans and other mammals