Probenemid
Brand names,
Probenemid
Analogs
Probenemid
Brand Names Mixture
Probenemid
Chemical_Formula
C13H19NO4S
Probenemid
RX_link
http://www.rxlist.com/cgi/generic/colbenemid.htm
Probenemid
fda sheet
Probenemid
msds (material safety sheet)
Probenemid
Synthesis Reference
No information avaliable
Probenemid
Molecular Weight
285.36 g/mol
Probenemid
Melting Point
195 oC
Probenemid
H2O Solubility
27.1 mg/L
Probenemid
State
Solid
Probenemid
LogP
2.324
Probenemid
Dosage Forms
Tablet
Probenemid
Indication
For the treatment of gout and high levels of uric acid in the blood
Probenemid
Pharmacology
Probenecid is a uricosuric and renal tubular blocking agent and is used in combination with colchicine to treat chronic gouty arthritis when complicated by frequent, recurrent acute attacks of gout. It inhibits the tubular reabsorption of urate, thus increasing the urinary excretion of uric acid and decreasing serum urate levels. Effective uricosuria reduces the miscible urate pool, retards urate deposition, and promotes resorption of urate deposits.
Probenemid
Absorption
No information avaliable
Probenemid
side effects and Toxicity
No information avaliable
Probenemid
Patient Information
No information avaliable
Probenemid
Organisms Affected
Humans and other mammals