Polycillin-PRB
Brand names,
Polycillin-PRB
Analogs
Polycillin-PRB
Brand Names Mixture
Polycillin-PRB
Chemical_Formula
C13H19NO4S
Polycillin-PRB
RX_link
http://www.rxlist.com/cgi/generic/colbenemid.htm
Polycillin-PRB
fda sheet
Polycillin-PRB
msds (material safety sheet)
Polycillin-PRB
Synthesis Reference
No information avaliable
Polycillin-PRB
Molecular Weight
285.36 g/mol
Polycillin-PRB
Melting Point
195 oC
Polycillin-PRB
H2O Solubility
27.1 mg/L
Polycillin-PRB
State
Solid
Polycillin-PRB
LogP
2.324
Polycillin-PRB
Dosage Forms
Tablet
Polycillin-PRB
Indication
For the treatment of gout and high levels of uric acid in the blood
Polycillin-PRB
Pharmacology
Probenecid is a uricosuric and renal tubular blocking agent and is used in combination with colchicine to treat chronic gouty arthritis when complicated by frequent, recurrent acute attacks of gout. It inhibits the tubular reabsorption of urate, thus increasing the urinary excretion of uric acid and decreasing serum urate levels. Effective uricosuria reduces the miscible urate pool, retards urate deposition, and promotes resorption of urate deposits.
Polycillin-PRB
Absorption
No information avaliable
Polycillin-PRB
side effects and Toxicity
No information avaliable
Polycillin-PRB
Patient Information
No information avaliable
Polycillin-PRB
Organisms Affected
Humans and other mammals