Proben
Brand names,
Proben
Analogs
Proben
Brand Names Mixture
Proben
Chemical_Formula
C13H19NO4S
Proben
RX_link
http://www.rxlist.com/cgi/generic/colbenemid.htm
Proben
fda sheet
Proben
msds (material safety sheet)
Proben
Synthesis Reference
No information avaliable
Proben
Molecular Weight
285.36 g/mol
Proben
Melting Point
195 oC
Proben
H2O Solubility
27.1 mg/L
Proben
State
Solid
Proben
LogP
2.324
Proben
Dosage Forms
Tablet
Proben
Indication
For the treatment of gout and high levels of uric acid in the blood
Proben
Pharmacology
Probenecid is a uricosuric and renal tubular blocking agent and is used in combination with colchicine to treat chronic gouty arthritis when complicated by frequent, recurrent acute attacks of gout. It inhibits the tubular reabsorption of urate, thus increasing the urinary excretion of uric acid and decreasing serum urate levels. Effective uricosuria reduces the miscible urate pool, retards urate deposition, and promotes resorption of urate deposits.
Proben
Absorption
No information avaliable
Proben
side effects and Toxicity
No information avaliable
Proben
Patient Information
No information avaliable
Proben
Organisms Affected
Humans and other mammals