Uricosid
Brand names,
Uricosid
Analogs
Uricosid
Brand Names Mixture
Uricosid
Chemical_Formula
C13H19NO4S
Uricosid
RX_link
http://www.rxlist.com/cgi/generic/colbenemid.htm
Uricosid
fda sheet
Uricosid
msds (material safety sheet)
Uricosid
Synthesis Reference
No information avaliable
Uricosid
Molecular Weight
285.36 g/mol
Uricosid
Melting Point
195 oC
Uricosid
H2O Solubility
27.1 mg/L
Uricosid
State
Solid
Uricosid
LogP
2.324
Uricosid
Dosage Forms
Tablet
Uricosid
Indication
For the treatment of gout and high levels of uric acid in the blood
Uricosid
Pharmacology
Probenecid is a uricosuric and renal tubular blocking agent and is used in combination with colchicine to treat chronic gouty arthritis when complicated by frequent, recurrent acute attacks of gout. It inhibits the tubular reabsorption of urate, thus increasing the urinary excretion of uric acid and decreasing serum urate levels. Effective uricosuria reduces the miscible urate pool, retards urate deposition, and promotes resorption of urate deposits.
Uricosid
Absorption
No information avaliable
Uricosid
side effects and Toxicity
No information avaliable
Uricosid
Patient Information
No information avaliable
Uricosid
Organisms Affected
Humans and other mammals