Probecid
Brand names,
Probecid
Analogs
Probecid
Brand Names Mixture
Probecid
Chemical_Formula
C13H19NO4S
Probecid
RX_link
http://www.rxlist.com/cgi/generic/colbenemid.htm
Probecid
fda sheet
Probecid
msds (material safety sheet)
Probecid
Synthesis Reference
No information avaliable
Probecid
Molecular Weight
285.36 g/mol
Probecid
Melting Point
195 oC
Probecid
H2O Solubility
27.1 mg/L
Probecid
State
Solid
Probecid
LogP
2.324
Probecid
Dosage Forms
Tablet
Probecid
Indication
For the treatment of gout and high levels of uric acid in the blood
Probecid
Pharmacology
Probenecid is a uricosuric and renal tubular blocking agent and is used in combination with colchicine to treat chronic gouty arthritis when complicated by frequent, recurrent acute attacks of gout. It inhibits the tubular reabsorption of urate, thus increasing the urinary excretion of uric acid and decreasing serum urate levels. Effective uricosuria reduces the miscible urate pool, retards urate deposition, and promotes resorption of urate deposits.
Probecid
Absorption
No information avaliable
Probecid
side effects and Toxicity
No information avaliable
Probecid
Patient Information
No information avaliable
Probecid
Organisms Affected
Humans and other mammals