Tokiocillin
Brand names,
Tokiocillin
Analogs
Tokiocillin
Brand Names Mixture
- Pro Biosan Kit (Ampicillin + Probenecid)
- Synergistin Injectable Suspension (Ampicillin + Sulbactam (Sulbactam Benzathine))
Tokiocillin
Chemical_Formula
C16H19N3O4S
Tokiocillin
RX_link
http://www.rxlist.com/cgi/generic/ampicillin.htm
Tokiocillin
fda sheet
Tokiocillin
msds (material safety sheet)
Tokiocillin
Synthesis Reference
No information avaliable
Tokiocillin
Molecular Weight
349.406 g/mol
Tokiocillin
Melting Point
208 oC
Tokiocillin
H2O Solubility
1.01E+004 mg/L
Tokiocillin
State
Solid
Tokiocillin
LogP
1.35
Tokiocillin
Dosage Forms
Powder for solution
Tokiocillin
Indication
For treatment of infection (Respiratory, GI, UTI and meningitis) due to E. coli, P. mirabilis, enterococci, Shigella, S. typhosa and other Salmonella, nonpenicillinase-producing N. gononhoeae, H. influenzae, staphylococci, streptococci including streptoc
Tokiocillin
Pharmacology
Ampicillin is a penicillin beta-lactam antibiotic used in the treatment of bacterial infections caused by susceptible, usually gram-positive, organisms. The name "penicillin" can either refer to several variants of penicillin available, or to the group of antibiotics derived from the penicillins. Ampicillin has in vitro activity against gram-positive and gram-negative aerobic and anaerobic bacteria. The bactericidal activity of Ampicillin results from the inhibition of cell wall synthesis and is mediated through Ampicillin binding to penicillin binding proteins (PBPs). Ampicillin is stable against hydrolysis by a variety of beta-lactamases, including penicillinases, and cephalosporinases and extended spectrum beta-lactamases.
Tokiocillin
Absorption
No information avaliable
Tokiocillin
side effects and Toxicity
No information avaliable
Tokiocillin
Patient Information
1. The patient should inform the physician of any history of sensitivity to allergens, including previous
hypersensitivity reactions to penicillins and cephalosporins.
2. The patient should discontinue ampicillin and contact the physician immediately if any side effect occurs.
3. Ampicillin should be taken with a full glass (8 oz) of water, one-half hour before or two hours after
meals.
4. Diabetic patients should consult with the physician before changing diet or dosage of diabetes medication .
Tokiocillin
Organisms Affected
Enteric bacteria and other eubacteria