Bayer 5427
Brand names,
Bayer 5427
Analogs
Bayer 5427
Brand Names Mixture
- Pro Biosan Kit (Ampicillin + Probenecid)
- Synergistin Injectable Suspension (Ampicillin + Sulbactam (Sulbactam Benzathine))
Bayer 5427
Chemical_Formula
C16H19N3O4S
Bayer 5427
RX_link
http://www.rxlist.com/cgi/generic/ampicillin.htm
Bayer 5427
fda sheet
Bayer 5427
msds (material safety sheet)
Bayer 5427
Synthesis Reference
No information avaliable
Bayer 5427
Molecular Weight
349.406 g/mol
Bayer 5427
Melting Point
208 oC
Bayer 5427
H2O Solubility
1.01E+004 mg/L
Bayer 5427
State
Solid
Bayer 5427
LogP
1.35
Bayer 5427
Dosage Forms
Powder for solution
Bayer 5427
Indication
For treatment of infection (Respiratory, GI, UTI and meningitis) due to E. coli, P. mirabilis, enterococci, Shigella, S. typhosa and other Salmonella, nonpenicillinase-producing N. gononhoeae, H. influenzae, staphylococci, streptococci including streptoc
Bayer 5427
Pharmacology
Ampicillin is a penicillin beta-lactam antibiotic used in the treatment of bacterial infections caused by susceptible, usually gram-positive, organisms. The name "penicillin" can either refer to several variants of penicillin available, or to the group of antibiotics derived from the penicillins. Ampicillin has in vitro activity against gram-positive and gram-negative aerobic and anaerobic bacteria. The bactericidal activity of Ampicillin results from the inhibition of cell wall synthesis and is mediated through Ampicillin binding to penicillin binding proteins (PBPs). Ampicillin is stable against hydrolysis by a variety of beta-lactamases, including penicillinases, and cephalosporinases and extended spectrum beta-lactamases.
Bayer 5427
Absorption
No information avaliable
Bayer 5427
side effects and Toxicity
No information avaliable
Bayer 5427
Patient Information
1. The patient should inform the physician of any history of sensitivity to allergens, including previous
hypersensitivity reactions to penicillins and cephalosporins.
2. The patient should discontinue ampicillin and contact the physician immediately if any side effect occurs.
3. Ampicillin should be taken with a full glass (8 oz) of water, one-half hour before or two hours after
meals.
4. Diabetic patients should consult with the physician before changing diet or dosage of diabetes medication .
Bayer 5427
Organisms Affected
Enteric bacteria and other eubacteria