Reserpine
Brand names,
Reserpine
Analogs
Reserpine
Brand Names Mixture
- Hydropres 25 Tab (Hydrochlorothiazide + Reserpine)
- Hydropres 50 Tab (Hydrochlorothiazide + Reserpine)
- SER-AP-ES Tab (Hydralazine Hydrochloride + Hydrochlorothiazide + Reserpine)
Reserpine
Chemical_Formula
C33H40N2O9
Reserpine
RX_link
No information avaliable
Reserpine
fda sheet
Reserpine
msds (material safety sheet)
Reserpine
Synthesis Reference
No information avaliable
Reserpine
Molecular Weight
608.679 g/mol
Reserpine
Melting Point
264.5 oC
Reserpine
H2O Solubility
73 mg/L
Reserpine
State
Solid
Reserpine
LogP
3.32
Reserpine
Dosage Forms
Tablets
Reserpine
Indication
Foe the treatment of hypertension
Reserpine
Pharmacology
Reserpine is an adrenergic blocking agent used to treat mild to moderate hypertension via the disruption of norepinephrine vesicular storage. The antihypertensive actions of Reserpine are a result of its ability to deplete catecholamines from peripheral sympathetic nerve endings. These substances are normally involved in controlling heart rate, force of cardiac contraction and peripheral resistance.
Reserpine
Absorption
No information avaliable
Reserpine
side effects and Toxicity
Possible human carcinogen. May cause reproductive harm. ORL-RAT LD50 420 mg/kg; IPR-RAT LD50 44 mg/kg; IVN-RAT LD50 15 mg/kg; ORL-MUS LD50 200 mg/kg; SCU-MUS LD50 52 mg/kg; IPR-RBT LD50 7 mg/kg
Reserpine
Patient Information
No information avaliable
Reserpine
Organisms Affected
Humans and other mammals