Serpasil-Apresoline
Brand names,
Serpasil-Apresoline
Analogs
Serpasil-Apresoline
Brand Names Mixture
- Hydropres 25 Tab (Hydrochlorothiazide + Reserpine)
- Hydropres 50 Tab (Hydrochlorothiazide + Reserpine)
- SER-AP-ES Tab (Hydralazine Hydrochloride + Hydrochlorothiazide + Reserpine)
Serpasil-Apresoline
Chemical_Formula
C33H40N2O9
Serpasil-Apresoline
RX_link
No information avaliable
Serpasil-Apresoline
fda sheet
Serpasil-Apresoline
msds (material safety sheet)
Serpasil-Apresoline
Synthesis Reference
No information avaliable
Serpasil-Apresoline
Molecular Weight
608.679 g/mol
Serpasil-Apresoline
Melting Point
264.5 oC
Serpasil-Apresoline
H2O Solubility
73 mg/L
Serpasil-Apresoline
State
Solid
Serpasil-Apresoline
LogP
3.32
Serpasil-Apresoline
Dosage Forms
Tablets
Serpasil-Apresoline
Indication
Foe the treatment of hypertension
Serpasil-Apresoline
Pharmacology
Reserpine is an adrenergic blocking agent used to treat mild to moderate hypertension via the disruption of norepinephrine vesicular storage. The antihypertensive actions of Reserpine are a result of its ability to deplete catecholamines from peripheral sympathetic nerve endings. These substances are normally involved in controlling heart rate, force of cardiac contraction and peripheral resistance.
Serpasil-Apresoline
Absorption
No information avaliable
Serpasil-Apresoline
side effects and Toxicity
Possible human carcinogen. May cause reproductive harm. ORL-RAT LD50 420 mg/kg; IPR-RAT LD50 44 mg/kg; IVN-RAT LD50 15 mg/kg; ORL-MUS LD50 200 mg/kg; SCU-MUS LD50 52 mg/kg; IPR-RBT LD50 7 mg/kg
Serpasil-Apresoline
Patient Information
No information avaliable
Serpasil-Apresoline
Organisms Affected
Humans and other mammals