Hiserpia
Brand names,
Hiserpia
Analogs
Hiserpia
Brand Names Mixture
- Hydropres 25 Tab (Hydrochlorothiazide + Reserpine)
- Hydropres 50 Tab (Hydrochlorothiazide + Reserpine)
- SER-AP-ES Tab (Hydralazine Hydrochloride + Hydrochlorothiazide + Reserpine)
Hiserpia
Chemical_Formula
C33H40N2O9
Hiserpia
RX_link
No information avaliable
Hiserpia
fda sheet
Hiserpia
msds (material safety sheet)
Hiserpia
Synthesis Reference
No information avaliable
Hiserpia
Molecular Weight
608.679 g/mol
Hiserpia
Melting Point
264.5 oC
Hiserpia
H2O Solubility
73 mg/L
Hiserpia
State
Solid
Hiserpia
LogP
3.32
Hiserpia
Dosage Forms
Tablets
Hiserpia
Indication
Foe the treatment of hypertension
Hiserpia
Pharmacology
Reserpine is an adrenergic blocking agent used to treat mild to moderate hypertension via the disruption of norepinephrine vesicular storage. The antihypertensive actions of Reserpine are a result of its ability to deplete catecholamines from peripheral sympathetic nerve endings. These substances are normally involved in controlling heart rate, force of cardiac contraction and peripheral resistance.
Hiserpia
Absorption
No information avaliable
Hiserpia
side effects and Toxicity
Possible human carcinogen. May cause reproductive harm. ORL-RAT LD50 420 mg/kg; IPR-RAT LD50 44 mg/kg; IVN-RAT LD50 15 mg/kg; ORL-MUS LD50 200 mg/kg; SCU-MUS LD50 52 mg/kg; IPR-RBT LD50 7 mg/kg
Hiserpia
Patient Information
No information avaliable
Hiserpia
Organisms Affected
Humans and other mammals