Serpalan
Brand names,
Serpalan
Analogs
Serpalan
Brand Names Mixture
- Hydropres 25 Tab (Hydrochlorothiazide + Reserpine)
- Hydropres 50 Tab (Hydrochlorothiazide + Reserpine)
- SER-AP-ES Tab (Hydralazine Hydrochloride + Hydrochlorothiazide + Reserpine)
Serpalan
Chemical_Formula
C33H40N2O9
Serpalan
RX_link
No information avaliable
Serpalan
fda sheet
Serpalan
msds (material safety sheet)
Serpalan
Synthesis Reference
No information avaliable
Serpalan
Molecular Weight
608.679 g/mol
Serpalan
Melting Point
264.5 oC
Serpalan
H2O Solubility
73 mg/L
Serpalan
State
Solid
Serpalan
LogP
3.32
Serpalan
Dosage Forms
Tablets
Serpalan
Indication
Foe the treatment of hypertension
Serpalan
Pharmacology
Reserpine is an adrenergic blocking agent used to treat mild to moderate hypertension via the disruption of norepinephrine vesicular storage. The antihypertensive actions of Reserpine are a result of its ability to deplete catecholamines from peripheral sympathetic nerve endings. These substances are normally involved in controlling heart rate, force of cardiac contraction and peripheral resistance.
Serpalan
Absorption
No information avaliable
Serpalan
side effects and Toxicity
Possible human carcinogen. May cause reproductive harm. ORL-RAT LD50 420 mg/kg; IPR-RAT LD50 44 mg/kg; IVN-RAT LD50 15 mg/kg; ORL-MUS LD50 200 mg/kg; SCU-MUS LD50 52 mg/kg; IPR-RBT LD50 7 mg/kg
Serpalan
Patient Information
No information avaliable
Serpalan
Organisms Affected
Humans and other mammals