Serpasil
Brand names,
Serpasil
Analogs
Serpasil
Brand Names Mixture
- Hydropres 25 Tab (Hydrochlorothiazide + Reserpine)
- Hydropres 50 Tab (Hydrochlorothiazide + Reserpine)
- SER-AP-ES Tab (Hydralazine Hydrochloride + Hydrochlorothiazide + Reserpine)
Serpasil
Chemical_Formula
C33H40N2O9
Serpasil
RX_link
No information avaliable
Serpasil
fda sheet
Serpasil
msds (material safety sheet)
Serpasil
Synthesis Reference
No information avaliable
Serpasil
Molecular Weight
608.679 g/mol
Serpasil
Melting Point
264.5 oC
Serpasil
H2O Solubility
73 mg/L
Serpasil
State
Solid
Serpasil
LogP
3.32
Serpasil
Dosage Forms
Tablets
Serpasil
Indication
Foe the treatment of hypertension
Serpasil
Pharmacology
Reserpine is an adrenergic blocking agent used to treat mild to moderate hypertension via the disruption of norepinephrine vesicular storage. The antihypertensive actions of Reserpine are a result of its ability to deplete catecholamines from peripheral sympathetic nerve endings. These substances are normally involved in controlling heart rate, force of cardiac contraction and peripheral resistance.
Serpasil
Absorption
No information avaliable
Serpasil
side effects and Toxicity
Possible human carcinogen. May cause reproductive harm. ORL-RAT LD50 420 mg/kg; IPR-RAT LD50 44 mg/kg; IVN-RAT LD50 15 mg/kg; ORL-MUS LD50 200 mg/kg; SCU-MUS LD50 52 mg/kg; IPR-RBT LD50 7 mg/kg
Serpasil
Patient Information
No information avaliable
Serpasil
Organisms Affected
Humans and other mammals