Dralserp
Brand names,
Dralserp
Analogs
Dralserp
Brand Names Mixture
- Hydropres 25 Tab (Hydrochlorothiazide + Reserpine)
- Hydropres 50 Tab (Hydrochlorothiazide + Reserpine)
- SER-AP-ES Tab (Hydralazine Hydrochloride + Hydrochlorothiazide + Reserpine)
Dralserp
Chemical_Formula
C33H40N2O9
Dralserp
RX_link
No information avaliable
Dralserp
fda sheet
Dralserp
msds (material safety sheet)
Dralserp
Synthesis Reference
No information avaliable
Dralserp
Molecular Weight
608.679 g/mol
Dralserp
Melting Point
264.5 oC
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H2O Solubility
73 mg/L
Dralserp
State
Solid
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LogP
3.32
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Dosage Forms
Tablets
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Indication
Foe the treatment of hypertension
Dralserp
Pharmacology
Reserpine is an adrenergic blocking agent used to treat mild to moderate hypertension via the disruption of norepinephrine vesicular storage. The antihypertensive actions of Reserpine are a result of its ability to deplete catecholamines from peripheral sympathetic nerve endings. These substances are normally involved in controlling heart rate, force of cardiac contraction and peripheral resistance.
Dralserp
Absorption
No information avaliable
Dralserp
side effects and Toxicity
Possible human carcinogen. May cause reproductive harm. ORL-RAT LD50 420 mg/kg; IPR-RAT LD50 44 mg/kg; IVN-RAT LD50 15 mg/kg; ORL-MUS LD50 200 mg/kg; SCU-MUS LD50 52 mg/kg; IPR-RBT LD50 7 mg/kg
Dralserp
Patient Information
No information avaliable
Dralserp
Organisms Affected
Humans and other mammals