Hydrap-ES
Brand names,
Hydrap-ES
Analogs
Hydrap-ES
Brand Names Mixture
- Hydropres 25 Tab (Hydrochlorothiazide + Reserpine)
- Hydropres 50 Tab (Hydrochlorothiazide + Reserpine)
- SER-AP-ES Tab (Hydralazine Hydrochloride + Hydrochlorothiazide + Reserpine)
Hydrap-ES
Chemical_Formula
C33H40N2O9
Hydrap-ES
RX_link
No information avaliable
Hydrap-ES
fda sheet
Hydrap-ES
msds (material safety sheet)
Hydrap-ES
Synthesis Reference
No information avaliable
Hydrap-ES
Molecular Weight
608.679 g/mol
Hydrap-ES
Melting Point
264.5 oC
Hydrap-ES
H2O Solubility
73 mg/L
Hydrap-ES
State
Solid
Hydrap-ES
LogP
3.32
Hydrap-ES
Dosage Forms
Tablets
Hydrap-ES
Indication
Foe the treatment of hypertension
Hydrap-ES
Pharmacology
Reserpine is an adrenergic blocking agent used to treat mild to moderate hypertension via the disruption of norepinephrine vesicular storage. The antihypertensive actions of Reserpine are a result of its ability to deplete catecholamines from peripheral sympathetic nerve endings. These substances are normally involved in controlling heart rate, force of cardiac contraction and peripheral resistance.
Hydrap-ES
Absorption
No information avaliable
Hydrap-ES
side effects and Toxicity
Possible human carcinogen. May cause reproductive harm. ORL-RAT LD50 420 mg/kg; IPR-RAT LD50 44 mg/kg; IVN-RAT LD50 15 mg/kg; ORL-MUS LD50 200 mg/kg; SCU-MUS LD50 52 mg/kg; IPR-RBT LD50 7 mg/kg
Hydrap-ES
Patient Information
No information avaliable
Hydrap-ES
Organisms Affected
Humans and other mammals