Serpate
Brand names,
Serpate
Analogs
Serpate
Brand Names Mixture
- Hydropres 25 Tab (Hydrochlorothiazide + Reserpine)
- Hydropres 50 Tab (Hydrochlorothiazide + Reserpine)
- SER-AP-ES Tab (Hydralazine Hydrochloride + Hydrochlorothiazide + Reserpine)
Serpate
Chemical_Formula
C33H40N2O9
Serpate
RX_link
No information avaliable
Serpate
fda sheet
Serpate
msds (material safety sheet)
Serpate
Synthesis Reference
No information avaliable
Serpate
Molecular Weight
608.679 g/mol
Serpate
Melting Point
264.5 oC
Serpate
H2O Solubility
73 mg/L
Serpate
State
Solid
Serpate
LogP
3.32
Serpate
Dosage Forms
Tablets
Serpate
Indication
Foe the treatment of hypertension
Serpate
Pharmacology
Reserpine is an adrenergic blocking agent used to treat mild to moderate hypertension via the disruption of norepinephrine vesicular storage. The antihypertensive actions of Reserpine are a result of its ability to deplete catecholamines from peripheral sympathetic nerve endings. These substances are normally involved in controlling heart rate, force of cardiac contraction and peripheral resistance.
Serpate
Absorption
No information avaliable
Serpate
side effects and Toxicity
Possible human carcinogen. May cause reproductive harm. ORL-RAT LD50 420 mg/kg; IPR-RAT LD50 44 mg/kg; IVN-RAT LD50 15 mg/kg; ORL-MUS LD50 200 mg/kg; SCU-MUS LD50 52 mg/kg; IPR-RBT LD50 7 mg/kg
Serpate
Patient Information
No information avaliable
Serpate
Organisms Affected
Humans and other mammals