Serpalan (TN)
Brand names,
Serpalan (TN)
Analogs
Serpalan (TN)
Brand Names Mixture
- Hydropres 25 Tab (Hydrochlorothiazide + Reserpine)
- Hydropres 50 Tab (Hydrochlorothiazide + Reserpine)
- SER-AP-ES Tab (Hydralazine Hydrochloride + Hydrochlorothiazide + Reserpine)
Serpalan (TN)
Chemical_Formula
C33H40N2O9
Serpalan (TN)
RX_link
No information avaliable
Serpalan (TN)
fda sheet
Serpalan (TN)
msds (material safety sheet)
Serpalan (TN)
Synthesis Reference
No information avaliable
Serpalan (TN)
Molecular Weight
608.679 g/mol
Serpalan (TN)
Melting Point
264.5 oC
Serpalan (TN)
H2O Solubility
73 mg/L
Serpalan (TN)
State
Solid
Serpalan (TN)
LogP
3.32
Serpalan (TN)
Dosage Forms
Tablets
Serpalan (TN)
Indication
Foe the treatment of hypertension
Serpalan (TN)
Pharmacology
Reserpine is an adrenergic blocking agent used to treat mild to moderate hypertension via the disruption of norepinephrine vesicular storage. The antihypertensive actions of Reserpine are a result of its ability to deplete catecholamines from peripheral sympathetic nerve endings. These substances are normally involved in controlling heart rate, force of cardiac contraction and peripheral resistance.
Serpalan (TN)
Absorption
No information avaliable
Serpalan (TN)
side effects and Toxicity
Possible human carcinogen. May cause reproductive harm. ORL-RAT LD50 420 mg/kg; IPR-RAT LD50 44 mg/kg; IVN-RAT LD50 15 mg/kg; ORL-MUS LD50 200 mg/kg; SCU-MUS LD50 52 mg/kg; IPR-RBT LD50 7 mg/kg
Serpalan (TN)
Patient Information
No information avaliable
Serpalan (TN)
Organisms Affected
Humans and other mammals