Probenecid
Brand names,
Probenecid
Analogs
Probenecid
Brand Names Mixture
Probenecid
Chemical_Formula
C13H19NO4S
Probenecid
RX_link
http://www.rxlist.com/cgi/generic/colbenemid.htm
Probenecid
fda sheet
Probenecid
msds (material safety sheet)
Probenecid
Synthesis Reference
No information avaliable
Probenecid
Molecular Weight
285.36 g/mol
Probenecid
Melting Point
195 oC
Probenecid
H2O Solubility
27.1 mg/L
Probenecid
State
Solid
Probenecid
LogP
2.324
Probenecid
Dosage Forms
Tablet
Probenecid
Indication
For the treatment of gout and high levels of uric acid in the blood
Probenecid
Pharmacology
Probenecid is a uricosuric and renal tubular blocking agent and is used in combination with colchicine to treat chronic gouty arthritis when complicated by frequent, recurrent acute attacks of gout. It inhibits the tubular reabsorption of urate, thus increasing the urinary excretion of uric acid and decreasing serum urate levels. Effective uricosuria reduces the miscible urate pool, retards urate deposition, and promotes resorption of urate deposits.
Probenecid
Absorption
No information avaliable
Probenecid
side effects and Toxicity
No information avaliable
Probenecid
Patient Information
No information avaliable
Probenecid
Organisms Affected
Humans and other mammals