Pressorol
Pressorol Brand names, Pressorol Analogs
Pressorol Brand Names Mixture
- No information avaliable
Pressorol Chemical_Formula
C9H13NO2
Pressorol RX_link
http://www.rxlist.com/cgi/generic2/metar.htm
Pressorol fda sheet
Pressorol msds (material safety sheet)
Pressorol Synthesis Reference
Brit. pat. 353,361 (1930 to I. G. Farben); Brit. pat. 396,951 (1932 to I. G. Farben); Swiss pat. 162,267 (1931 to I. G. Farben); U.S. pats. 1,948,162 ans 1,951,302; Hartung, U.S. pat. 1,995,709 (1935 to Sharp & Dohme)
Pressorol Molecular Weight
167.205 g/mol
Pressorol Melting Point
107.5 oC
Pressorol H2O Solubility
1000 g/L
Pressorol State
Solid
Pressorol LogP
0.6
Pressorol Dosage Forms
Intramuscular injection; Intravenous injection
Pressorol Indication
For the treatment and prevention of hypotension due to hemorrhage, spinal anesthesia, and shock associated with brain damage
Pressorol Pharmacology
Metaraminol is a potent sympathomimetic amine that increases both systolic and diastolic blood pressure. Metaraminol is indicated for prevention and treatment of the acute hypotensive state occurring with spinal anesthesia. It is also indicated as adjunctive treatment of hypotension due to hemorrhage, reactions to medications, surgical complications, and shock associated with brain damage due to trauma or tumor. Metaraminol acts on both α1-adrenergic receptors but appears to have no effect on β-adrenergic receptors. It acts by increasing the force of the heart's pumping action as well as constricting peripheral blood vessels.
Pressorol Absorption
The effect starts 1-2 min after IV injection, 10 min after IM injection, 5-20 min after subcutaneous injection.
Pressorol side effects and Toxicity
LD50=240 mg/kg (rat, oral); LD50=99 mg/kg (mouse, oral)
Pressorol Patient Information
Pressorol Organisms Affected
Humans and other mammals
