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Aramine Brand names, Aramine Analogs

Aramine Brand Names Mixture

  • No information avaliable

Aramine Chemical_Formula


Aramine RX_link

Aramine fda sheet

Aramine msds (material safety sheet)

Aramine MSDS

Aramine Synthesis Reference

Brit. pat. 353,361 (1930 to I. G. Farben); Brit. pat. 396,951 (1932 to I. G. Farben); Swiss pat. 162,267 (1931 to I. G. Farben); U.S. pats. 1,948,162 ans 1,951,302; Hartung, U.S. pat. 1,995,709 (1935 to Sharp & Dohme)

Aramine Molecular Weight

167.205 g/mol

Aramine Melting Point

107.5 oC

Aramine H2O Solubility

1000 g/L

Aramine State


Aramine LogP


Aramine Dosage Forms

Intramuscular injection; Intravenous injection

Aramine Indication

For the treatment and prevention of hypotension due to hemorrhage, spinal anesthesia, and shock associated with brain damage

Aramine Pharmacology

Metaraminol is a potent sympathomimetic amine that increases both systolic and diastolic blood pressure. Metaraminol is indicated for prevention and treatment of the acute hypotensive state occurring with spinal anesthesia. It is also indicated as adjunctive treatment of hypotension due to hemorrhage, reactions to medications, surgical complications, and shock associated with brain damage due to trauma or tumor. Metaraminol acts on both α1-adrenergic receptors but appears to have no effect on β-adrenergic receptors. It acts by increasing the force of the heart's pumping action as well as constricting peripheral blood vessels.

Aramine Absorption

The effect starts 1-2 min after IV injection, 10 min after IM injection, 5-20 min after subcutaneous injection.

Aramine side effects and Toxicity

LD50=240 mg/kg (rat, oral); LD50=99 mg/kg (mouse, oral)

Aramine Patient Information

Aramine Organisms Affected

Humans and other mammals