Metaradrine en es it fr

Metaradrine Brand names, Metaradrine Analogs

Metaradrine Brand Names Mixture

  • No information avaliable

Metaradrine Chemical_Formula


Metaradrine RX_link

Metaradrine fda sheet

Metaradrine msds (material safety sheet)

Metaradrine MSDS

Metaradrine Synthesis Reference

Brit. pat. 353,361 (1930 to I. G. Farben); Brit. pat. 396,951 (1932 to I. G. Farben); Swiss pat. 162,267 (1931 to I. G. Farben); U.S. pats. 1,948,162 ans 1,951,302; Hartung, U.S. pat. 1,995,709 (1935 to Sharp & Dohme)

Metaradrine Molecular Weight

167.205 g/mol

Metaradrine Melting Point

107.5 oC

Metaradrine H2O Solubility

1000 g/L

Metaradrine State


Metaradrine LogP


Metaradrine Dosage Forms

Intramuscular injection; Intravenous injection

Metaradrine Indication

For the treatment and prevention of hypotension due to hemorrhage, spinal anesthesia, and shock associated with brain damage

Metaradrine Pharmacology

Metaraminol is a potent sympathomimetic amine that increases both systolic and diastolic blood pressure. Metaraminol is indicated for prevention and treatment of the acute hypotensive state occurring with spinal anesthesia. It is also indicated as adjunctive treatment of hypotension due to hemorrhage, reactions to medications, surgical complications, and shock associated with brain damage due to trauma or tumor. Metaraminol acts on both α1-adrenergic receptors but appears to have no effect on β-adrenergic receptors. It acts by increasing the force of the heart's pumping action as well as constricting peripheral blood vessels.

Metaradrine Absorption

The effect starts 1-2 min after IV injection, 10 min after IM injection, 5-20 min after subcutaneous injection.

Metaradrine side effects and Toxicity

LD50=240 mg/kg (rat, oral); LD50=99 mg/kg (mouse, oral)

Metaradrine Patient Information

Metaradrine Organisms Affected

Humans and other mammals