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Pressonex Brand names, Pressonex Analogs

Pressonex Brand Names Mixture

  • No information avaliable

Pressonex Chemical_Formula

C9H13NO2

Pressonex RX_link

http://www.rxlist.com/cgi/generic2/metar.htm

Pressonex fda sheet

Pressonex msds (material safety sheet)

Pressonex MSDS

Pressonex Synthesis Reference

Brit. pat. 353,361 (1930 to I. G. Farben); Brit. pat. 396,951 (1932 to I. G. Farben); Swiss pat. 162,267 (1931 to I. G. Farben); U.S. pats. 1,948,162 ans 1,951,302; Hartung, U.S. pat. 1,995,709 (1935 to Sharp & Dohme)

Pressonex Molecular Weight

167.205 g/mol

Pressonex Melting Point

107.5 oC

Pressonex H2O Solubility

1000 g/L

Pressonex State

Solid

Pressonex LogP

0.6

Pressonex Dosage Forms

Intramuscular injection; Intravenous injection

Pressonex Indication

For the treatment and prevention of hypotension due to hemorrhage, spinal anesthesia, and shock associated with brain damage

Pressonex Pharmacology

Metaraminol is a potent sympathomimetic amine that increases both systolic and diastolic blood pressure. Metaraminol is indicated for prevention and treatment of the acute hypotensive state occurring with spinal anesthesia. It is also indicated as adjunctive treatment of hypotension due to hemorrhage, reactions to medications, surgical complications, and shock associated with brain damage due to trauma or tumor. Metaraminol acts on both α1-adrenergic receptors but appears to have no effect on β-adrenergic receptors. It acts by increasing the force of the heart's pumping action as well as constricting peripheral blood vessels.

Pressonex Absorption

The effect starts 1-2 min after IV injection, 10 min after IM injection, 5-20 min after subcutaneous injection.

Pressonex side effects and Toxicity

LD50=240 mg/kg (rat, oral); LD50=99 mg/kg (mouse, oral)

Pressonex Patient Information

Pressonex Organisms Affected

Humans and other mammals