M-Hydroxy Norephedrine

M-Hydroxy Norephedrine Brand names, M-Hydroxy Norephedrine Analogs

M-Hydroxy Norephedrine Brand Names Mixture

No information avaliable

M-Hydroxy Norephedrine Chemical_Formula

C₉H₁₃NO₂

M-Hydroxy Norephedrine RX_link

http://www.rxlist.com/cgi/generic2/metar.htm

M-Hydroxy Norephedrine fda sheet

M-Hydroxy Norephedrine msds (material safety sheet)

M-Hydroxy_Norephedrine MSDS

M-Hydroxy Norephedrine Synthesis Reference

Brit. pat. 353,361 (1930 to I. G. Farben); Brit. pat. 396,951 (1932 to I. G. Farben); Swiss pat. 162,267 (1931 to I. G. Farben); U.S. pats. 1,948,162 ans 1,951,302; Hartung, U.S. pat. 1,995,709 (1935 to Sharp & Dohme)

M-Hydroxy Norephedrine Molecular Weight

167.205 g/mol

M-Hydroxy Norephedrine Melting Point

107.5 ^oC

M-Hydroxy Norephedrine H₂O Solubility

1000 g/L

M-Hydroxy Norephedrine State

Solid

M-Hydroxy Norephedrine LogP

0.6

M-Hydroxy Norephedrine Dosage Forms

Intramuscular injection; Intravenous injection

M-Hydroxy Norephedrine Indication

For the treatment and prevention of hypotension due to hemorrhage, spinal anesthesia, and shock associated with brain damage

M-Hydroxy Norephedrine Pharmacology

Metaraminol is a potent sympathomimetic amine that increases both systolic and diastolic blood pressure. Metaraminol is indicated for prevention and treatment of the acute hypotensive state occurring with spinal anesthesia. It is also indicated as adjunctive treatment of hypotension due to hemorrhage, reactions to medications, surgical complications, and shock associated with brain damage due to trauma or tumor. Metaraminol acts on both α1-adrenergic receptors but appears to have no effect on β-adrenergic receptors. It acts by increasing the force of the heart's pumping action as well as constricting peripheral blood vessels.

M-Hydroxy Norephedrine Absorption

The effect starts 1-2 min after IV injection, 10 min after IM injection, 5-20 min after subcutaneous injection.

M-Hydroxy Norephedrine side effects and Toxicity

LD₅₀=240 mg/kg (rat, oral); LD₅₀=99 mg/kg (mouse, oral)

M-Hydroxy Norephedrine Patient Information

M-Hydroxy Norephedrine Organisms Affected

Humans and other mammals