Metaraminol Bitartrate en es it fr

Metaraminol Bitartrate Brand names, Metaraminol Bitartrate Analogs

Metaraminol Bitartrate Brand Names Mixture

  • No information avaliable

Metaraminol Bitartrate Chemical_Formula

C9H13NO2

Metaraminol Bitartrate RX_link

http://www.rxlist.com/cgi/generic2/metar.htm

Metaraminol Bitartrate fda sheet

Metaraminol Bitartrate msds (material safety sheet)

Metaraminol_Bitartrate MSDS

Metaraminol Bitartrate Synthesis Reference

Brit. pat. 353,361 (1930 to I. G. Farben); Brit. pat. 396,951 (1932 to I. G. Farben); Swiss pat. 162,267 (1931 to I. G. Farben); U.S. pats. 1,948,162 ans 1,951,302; Hartung, U.S. pat. 1,995,709 (1935 to Sharp & Dohme)

Metaraminol Bitartrate Molecular Weight

167.205 g/mol

Metaraminol Bitartrate Melting Point

107.5 oC

Metaraminol Bitartrate H2O Solubility

1000 g/L

Metaraminol Bitartrate State

Solid

Metaraminol Bitartrate LogP

0.6

Metaraminol Bitartrate Dosage Forms

Intramuscular injection; Intravenous injection

Metaraminol Bitartrate Indication

For the treatment and prevention of hypotension due to hemorrhage, spinal anesthesia, and shock associated with brain damage

Metaraminol Bitartrate Pharmacology

Metaraminol is a potent sympathomimetic amine that increases both systolic and diastolic blood pressure. Metaraminol is indicated for prevention and treatment of the acute hypotensive state occurring with spinal anesthesia. It is also indicated as adjunctive treatment of hypotension due to hemorrhage, reactions to medications, surgical complications, and shock associated with brain damage due to trauma or tumor. Metaraminol acts on both α1-adrenergic receptors but appears to have no effect on β-adrenergic receptors. It acts by increasing the force of the heart's pumping action as well as constricting peripheral blood vessels.

Metaraminol Bitartrate Absorption

The effect starts 1-2 min after IV injection, 10 min after IM injection, 5-20 min after subcutaneous injection.

Metaraminol Bitartrate side effects and Toxicity

LD50=240 mg/kg (rat, oral); LD50=99 mg/kg (mouse, oral)

Metaraminol Bitartrate Patient Information

Metaraminol Bitartrate Organisms Affected

Humans and other mammals