M-Hydroxyphenylpropanolamine en es it fr

M-Hydroxyphenylpropanolamine Brand names, M-Hydroxyphenylpropanolamine Analogs

M-Hydroxyphenylpropanolamine Brand Names Mixture

  • No information avaliable

M-Hydroxyphenylpropanolamine Chemical_Formula


M-Hydroxyphenylpropanolamine RX_link


M-Hydroxyphenylpropanolamine fda sheet

M-Hydroxyphenylpropanolamine msds (material safety sheet)

M-Hydroxyphenylpropanolamine MSDS

M-Hydroxyphenylpropanolamine Synthesis Reference

Brit. pat. 353,361 (1930 to I. G. Farben); Brit. pat. 396,951 (1932 to I. G. Farben); Swiss pat. 162,267 (1931 to I. G. Farben); U.S. pats. 1,948,162 ans 1,951,302; Hartung, U.S. pat. 1,995,709 (1935 to Sharp & Dohme)

M-Hydroxyphenylpropanolamine Molecular Weight

167.205 g/mol

M-Hydroxyphenylpropanolamine Melting Point

107.5 oC

M-Hydroxyphenylpropanolamine H2O Solubility

1000 g/L

M-Hydroxyphenylpropanolamine State


M-Hydroxyphenylpropanolamine LogP


M-Hydroxyphenylpropanolamine Dosage Forms

Intramuscular injection; Intravenous injection

M-Hydroxyphenylpropanolamine Indication

For the treatment and prevention of hypotension due to hemorrhage, spinal anesthesia, and shock associated with brain damage

M-Hydroxyphenylpropanolamine Pharmacology

Metaraminol is a potent sympathomimetic amine that increases both systolic and diastolic blood pressure. Metaraminol is indicated for prevention and treatment of the acute hypotensive state occurring with spinal anesthesia. It is also indicated as adjunctive treatment of hypotension due to hemorrhage, reactions to medications, surgical complications, and shock associated with brain damage due to trauma or tumor. Metaraminol acts on both α1-adrenergic receptors but appears to have no effect on β-adrenergic receptors. It acts by increasing the force of the heart's pumping action as well as constricting peripheral blood vessels.

M-Hydroxyphenylpropanolamine Absorption

The effect starts 1-2 min after IV injection, 10 min after IM injection, 5-20 min after subcutaneous injection.

M-Hydroxyphenylpropanolamine side effects and Toxicity

LD50=240 mg/kg (rat, oral); LD50=99 mg/kg (mouse, oral)

M-Hydroxyphenylpropanolamine Patient Information

M-Hydroxyphenylpropanolamine Organisms Affected

Humans and other mammals