Oxilapine
Oxilapine Brand names, Oxilapine Analogs
Oxilapine Brand Names Mixture
- No information avaliable
Oxilapine Chemical_Formula
C18H18ClN3O
Oxilapine RX_link
http://www.rxlist.com/cgi/generic2/loxapineoc.htm
Oxilapine fda sheet
Oxilapine msds (material safety sheet)
Oxilapine Synthesis Reference
Neth. pat. Appl. 6,406,089 corresp to Schmutz et al., U.S. pat. 3,546,226 (1964, 1970 both to Wander)
Oxilapine Molecular Weight
327.808 g/mol
Oxilapine Melting Point
109-110 oC
Oxilapine H2O Solubility
No information avaliable
Oxilapine State
Solid
Oxilapine LogP
3.162
Oxilapine Dosage Forms
Tablet; Capsule; Oral solution; IV solution; IM solution
Oxilapine Indication
For the management of the manifestations of psychotic disorders
Oxilapine Pharmacology
Loxapine, a dibenzoxazepine compound, represents a subclass of tricyclic antipsychotic agents, chemically distinct from the thioxanthenes, butyrophenones, and phenothiazines. Pharmacologically, Loxapine is a tranquilizer for which the exact mode of action has not been established.
Oxilapine Absorption
Systemic bioavailability of the parent drug was only about one third that after an equivalent intramuscular dose (25 mg base) in male volunteers
Oxilapine side effects and Toxicity
LD50=65 mg/kg (Orally in mice)
Oxilapine Patient Information
Oxilapine Organisms Affected
Humans and other mammals
