Loxitane
Loxitane Brand names, Loxitane Analogs
Loxitane Brand Names Mixture
- No information avaliable
Loxitane Chemical_Formula
C18H18ClN3O
Loxitane RX_link
http://www.rxlist.com/cgi/generic2/loxapineoc.htm
Loxitane fda sheet
Loxitane msds (material safety sheet)
Loxitane Synthesis Reference
Neth. pat. Appl. 6,406,089 corresp to Schmutz et al., U.S. pat. 3,546,226 (1964, 1970 both to Wander)
Loxitane Molecular Weight
327.808 g/mol
Loxitane Melting Point
109-110 oC
Loxitane H2O Solubility
No information avaliable
Loxitane State
Solid
Loxitane LogP
3.162
Loxitane Dosage Forms
Tablet; Capsule; Oral solution; IV solution; IM solution
Loxitane Indication
For the management of the manifestations of psychotic disorders
Loxitane Pharmacology
Loxapine, a dibenzoxazepine compound, represents a subclass of tricyclic antipsychotic agents, chemically distinct from the thioxanthenes, butyrophenones, and phenothiazines. Pharmacologically, Loxapine is a tranquilizer for which the exact mode of action has not been established.
Loxitane Absorption
Systemic bioavailability of the parent drug was only about one third that after an equivalent intramuscular dose (25 mg base) in male volunteers
Loxitane side effects and Toxicity
LD50=65 mg/kg (Orally in mice)
Loxitane Patient Information
Loxitane Organisms Affected
Humans and other mammals
