Dibenzacepin
Dibenzacepin Brand names, Dibenzacepin Analogs
Dibenzacepin Brand Names Mixture
- No information avaliable
Dibenzacepin Chemical_Formula
C18H18ClN3O
Dibenzacepin RX_link
http://www.rxlist.com/cgi/generic2/loxapineoc.htm
Dibenzacepin fda sheet
Dibenzacepin msds (material safety sheet)
Dibenzacepin Synthesis Reference
Neth. pat. Appl. 6,406,089 corresp to Schmutz et al., U.S. pat. 3,546,226 (1964, 1970 both to Wander)
Dibenzacepin Molecular Weight
327.808 g/mol
Dibenzacepin Melting Point
109-110 oC
Dibenzacepin H2O Solubility
No information avaliable
Dibenzacepin State
Solid
Dibenzacepin LogP
3.162
Dibenzacepin Dosage Forms
Tablet; Capsule; Oral solution; IV solution; IM solution
Dibenzacepin Indication
For the management of the manifestations of psychotic disorders
Dibenzacepin Pharmacology
Loxapine, a dibenzoxazepine compound, represents a subclass of tricyclic antipsychotic agents, chemically distinct from the thioxanthenes, butyrophenones, and phenothiazines. Pharmacologically, Loxapine is a tranquilizer for which the exact mode of action has not been established.
Dibenzacepin Absorption
Systemic bioavailability of the parent drug was only about one third that after an equivalent intramuscular dose (25 mg base) in male volunteers
Dibenzacepin side effects and Toxicity
LD50=65 mg/kg (Orally in mice)
Dibenzacepin Patient Information
Dibenzacepin Organisms Affected
Humans and other mammals
