Loxitane C
Brand names,
Loxitane C
Analogs
Loxitane C
Brand Names Mixture
Loxitane C
Chemical_Formula
C18H18ClN3O
Loxitane C
RX_link
http://www.rxlist.com/cgi/generic2/loxapineoc.htm
Loxitane C
fda sheet
Loxitane C
msds (material safety sheet)
Loxitane C
Synthesis Reference
Neth. pat. Appl. 6,406,089 corresp to Schmutz et al., U.S. pat. 3,546,226 (1964, 1970 both to Wander)
Loxitane C
Molecular Weight
327.808 g/mol
Loxitane C
Melting Point
109-110 oC
Loxitane C
H2O Solubility
No information avaliable
Loxitane C
State
Solid
Loxitane C
LogP
3.162
Loxitane C
Dosage Forms
Tablet; Capsule; Oral solution; IV solution; IM solution
Loxitane C
Indication
For the management of the manifestations of psychotic disorders
Loxitane C
Pharmacology
Loxapine, a dibenzoxazepine compound, represents a subclass of tricyclic antipsychotic agents, chemically distinct from the thioxanthenes, butyrophenones, and phenothiazines. Pharmacologically, Loxapine is a tranquilizer for which the exact mode of action has not been established.
Loxitane C
Absorption
Systemic bioavailability of the parent drug was only about one third that after an equivalent intramuscular dose (25 mg base) in male volunteers
Loxitane C
side effects and Toxicity
LD50=65 mg/kg (Orally in mice)
Loxitane C
Patient Information
Loxitane C
Organisms Affected
Humans and other mammals