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Loxepine Brand names, Loxepine Analogs

Loxepine Brand Names Mixture

  • No information avaliable

Loxepine Chemical_Formula

C18H18ClN3O

Loxepine RX_link

http://www.rxlist.com/cgi/generic2/loxapineoc.htm

Loxepine fda sheet

Loxepine msds (material safety sheet)

Loxepine Synthesis Reference

Neth. pat. Appl. 6,406,089 corresp to Schmutz et al., U.S. pat. 3,546,226 (1964, 1970 both to Wander)

Loxepine Molecular Weight

327.808 g/mol

Loxepine Melting Point

109-110 oC

Loxepine H2O Solubility

No information avaliable

Loxepine State

Solid

Loxepine LogP

3.162

Loxepine Dosage Forms

Tablet; Capsule; Oral solution; IV solution; IM solution

Loxepine Indication

For the management of the manifestations of psychotic disorders

Loxepine Pharmacology

Loxapine, a dibenzoxazepine compound, represents a subclass of tricyclic antipsychotic agents, chemically distinct from the thioxanthenes, butyrophenones, and phenothiazines. Pharmacologically, Loxapine is a tranquilizer for which the exact mode of action has not been established.

Loxepine Absorption

Systemic bioavailability of the parent drug was only about one third that after an equivalent intramuscular dose (25 mg base) in male volunteers

Loxepine side effects and Toxicity

LD50=65 mg/kg (Orally in mice)

Loxepine Patient Information

Loxepine Organisms Affected

Humans and other mammals