Cloxazepine
Cloxazepine Brand names, Cloxazepine Analogs
Cloxazepine Brand Names Mixture
- No information avaliable
Cloxazepine Chemical_Formula
C18H18ClN3O
Cloxazepine RX_link
http://www.rxlist.com/cgi/generic2/loxapineoc.htm
Cloxazepine fda sheet
Cloxazepine msds (material safety sheet)
Cloxazepine Synthesis Reference
Neth. pat. Appl. 6,406,089 corresp to Schmutz et al., U.S. pat. 3,546,226 (1964, 1970 both to Wander)
Cloxazepine Molecular Weight
327.808 g/mol
Cloxazepine Melting Point
109-110 oC
Cloxazepine H2O Solubility
No information avaliable
Cloxazepine State
Solid
Cloxazepine LogP
3.162
Cloxazepine Dosage Forms
Tablet; Capsule; Oral solution; IV solution; IM solution
Cloxazepine Indication
For the management of the manifestations of psychotic disorders
Cloxazepine Pharmacology
Loxapine, a dibenzoxazepine compound, represents a subclass of tricyclic antipsychotic agents, chemically distinct from the thioxanthenes, butyrophenones, and phenothiazines. Pharmacologically, Loxapine is a tranquilizer for which the exact mode of action has not been established.
Cloxazepine Absorption
Systemic bioavailability of the parent drug was only about one third that after an equivalent intramuscular dose (25 mg base) in male volunteers
Cloxazepine side effects and Toxicity
LD50=65 mg/kg (Orally in mice)
Cloxazepine Patient Information
Cloxazepine Organisms Affected
Humans and other mammals
