Megestrol

Megestrol Brand names, Megestrol Analogs

Megestrol Brand Names Mixture

No information avaliable

Megestrol Chemical_Formula

C₂₂H₃₀O₃

Megestrol RX_link

http://www.rxlist.com/cgi/generic4/megace_es.htm

Megestrol fda sheet

Megestrol FDA

Megestrol msds (material safety sheet)

Megestrol MSDS

Megestrol Synthesis Reference

No information avaliable

Megestrol Molecular Weight

342.472 g/mol

Megestrol Melting Point

218.0-220.0^oC

Megestrol H₂O Solubility

2 µg/mL (at 37°C for the acetate salt)

Megestrol State

Solid

Megestrol LogP

3.123

Megestrol Dosage Forms

Oral suspension containing 125 mg of megestrol acetate per mL; Tablet

Megestrol Indication

For the treatment of anorexia, cachexia, or an unexplained, significant weight loss in patients with a diagnosis of acquired immunodeficiency syndrome (AIDS). Also used to treat breast cancer, endometrial cancer, and prostate cancer in Canada and some other countries.

Megestrol Pharmacology

Megestrol is a synthetic progestin and has the same physiologic effects as natural progesterone. The precise mechanism of megestrol’s antianorexic and anticachetic effects is unknown. Initially developed as a contraceptive, it was first evaluated in breast cancer treatment in 1967.

Megestrol Absorption

Variable, but well absorbed orally.

Megestrol side effects and Toxicity

No serious unexpected side effects have resulted from studies involving megestrol acetate oral suspension administered in dosages as high as 1200 mg/day.

Megestrol Patient Information